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Name
ID
B6.Cg-Tg(K18-ACE2)2Prlmn/J
MGI:6389236
Phenotype annotations related to immune system
Darker colors indicate more annotations
Mouse Phenotypes
abnormal chemokine level
abnormal circulating chemokine level
abnormal circulating cytokine level
abnormal cytokine level
abnormal interferon level
abnormal interleukin level
abnormal tumor necrosis factor level
blood vessel inflammation
brain inflammation
bronchiolitis
conjunctivitis
cytokine storm
enhanced humoral immune response
increased circulating CXCL10 level
increased circulating interferon-gamma level
increased circulating interleukin-6 level
increased circulating interleukin-10 level
increased circulating tumor necrosis factor level
increased CXCL10 level
increased IgG level
increased IgM level
increased leukocyte cell number
increased lymphocyte cell number
increased macrophage cell number
increased neutrophil cell number
increased susceptibility to Coronaviridae infection
increased susceptibility to Coronaviridae infection induced morbidity/mortality
increased susceptibility to Orthomyxoviridae infection
increased susceptibility to viral infection
increased susceptibility to viral infection induced morbidity/mortality
increased T cell number
interstitial pneumonia
liver inflammation
lung inflammation
meningitis
meningoencephalitis
microgliosis
rhinitis
Availability Mouse Genotype
Tg(K18-ACE2)2Prlmn/0